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EMBO Practical Course_Computational analysis of protein-protein interactions: Sequences, networks and diseases


05/11/2018 - 10/11/2018 All day

Recent growth in protein-protein interaction (PPI) data provides massive opportunities for gaining biological insights, including the characterization of protein complexes and pathways. Many tools and resources exist to analyse and disseminate these data, but often bench scientists are not trained in them. In particular, they need to learn how to explore, manage, and interconnect these datasets. Given the importance of such techniques in several biomedical science disciplines, there is a major need for training in relevant tools without which bench scientists risk missing important insights from their own data. This EMBO Practical Course aims to train participants in bioinformatics techniques for gaining a network perspective on PPIs, predicting and analysing them, highlighting differences between globular (protein "domains") and non-globular (intrinsically disordered peptide) modules, and working with large datasets. Ideal participants for this course are bench scientists who are working to obtain data related to protein-protein interactions, or already have such data they want to analyse. One of the focuses of this course will be teaching the importance of PPIs in biological systems, and how bioinformatics tools can be harnessed for understanding and controlling physiological states and when these states are perturbed by disease. Keeping these aspects into consideration, disease datasets are integrated into the training materials. We will teach state-of-the-art bioinformatics tools, including Cytoscape, STRING, ELM, IUPRED and Chimera2. We will focus on integrating experimental interaction data (XL-MS, Bio-ID) into PPI networks. Many of the publicly available tools are highly interconnected and we will show participants how to take advantage of this integration.

Place

The National Research Council (CNR) Piazzale Aldo Moro, 7 00185 Rome, Italy

RESOURCES

- EMBO Practical Course

other events


Intrinsically disordered proteins ELIXIR User Community kickoff meeting


31/10/2018
09:00 - 18:00

Wednesday 31 October 2018, 09:00 to 18:00 (CET) at Department of Biomedical Sciences, University of Padua – Vallisneri building, Via Ugo Bassi 58/B, PD, 35131, Italy will take place the Intrinsically disordered proteins ELIXIR User Community kickoff meeting. This kickoff meeting will discuss a recently approved ELIXIR User Community on the topic of Intrinsically Disordered Proteins (IDPs). Over … Continue reading Intrinsically disordered proteins ELIXIR User Community kickoff meeting

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Nettab Satellite event: Adopting Open Source Software FAIR Practices


22/10/2018
All day

The “ELIXIR Training Platform” is partnering with The Carpentries (Software and Data Carpentry) to train life science researchers in computing and data management skills. The “ELIXIR Software development best practices” group, which is part of the ELIXIR Tools Platform, has proposed “Four simple recommendations to encourage best practices in research software” aiming to help researchers … Continue reading Nettab Satellite event: Adopting Open Source Software FAIR Practices

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